Kayle Leogrande (born March 29, 1977) is an American road racing cyclist, who is currently suspended from the sport. Leogrande was the 2006 winner of the United States National Amateur Criterium Championships, and spent two years with the infamous Rock Racing team, having turned professional in 2005 with US domestic squad Jelly Belly–Pool Gel.

Leogrande was embroiled in a doping scandal in 2008, when it was alleged that he confessed his use of performance-enhancing drugs to a team staffer when competing at Superweek on July 26, 2007. Leogrande vigorously contested the charges brought against him by the United States Anti-Doping Agency (USADA), but was suspended for two years after a three-member arbitration panel concluded he had used EPO. Leogrande completed his suspension in late 2010, and announced his intention to compete again in a video released on YouTube.

In 2017 Leogrande was banned by USADA for a further 8 years after testing positive for seven substances at an amateur race.