Francisco Martínez may refer to:

• Francisco Martínez (basketball) (1910–1993), Mexican basketball player, competed for Mexico at the 1936 Summer Olympics
• Francisco Martínez (boxer) (born 1976), Mexican Olympic boxer
• Francisco Martínez de Baeza (fl. 1634–1639), colonial governor of New Mexico from 1634 to 1637
• Francisco Martínez Marina (1754–1833), Spanish jurist, historian and priest
• Francisco Martínez Soria (1902–1982), Spanish actor
• Francisco Martínez de la Rosa (1787–1862), Spanish statesman and dramatist
• Francisco Martínez (footballer, born 1986), Argentine footballer
• Francisco Martínez (footballer, born 1988), Andorran footballer
• Francisco Martínez (footballer, born 1990), Argentine footballer
• Kiko Martínez (born 1984), Spanish professional boxer
• Francisco Martínez Martínez (born 1950), Mexican politician
• Francisco José Martínez (born 1983), Spanish cyclist
• Francisco Martínez Romero (1993–2021), Chilean protester and juggler