James & Browne was a British automobile manufacturer, based in Hammersmith, London between 1898 and 1910. The enterprise started in 1896 as a partnership between John Melville James, a former racing cyclist, and Tom Bousquet Browne. This partnership was dissolved in 1898 with Browne continuing the business with Francis Leigh Martineau under the James and Browne name.

The James & Browne factory was located at the Chiswick end of King's Street in West London, and there was a car showroom on Oxford Street.

The early cars had an unusual engine layout with the flywheel between the cylinders. The engines were mid-mounted in the chassis, and the cylinders were horizontal. Drive was to the rear wheels via a 4-speed gearbox and chain. The gearbox is in 2 parts, linked by a connecting rod, the left one containing 2nd and 4th gear, and the right 1st, 3rd and reverse.

The 2-cylinder engine is rated at 9 HP, and is just over 2.5 liters in size. A total-loss oiling system is used on the car, lubricating 6 main oil-ways. James & Browne also launched a 4-cylinder version (16 HP), of a similar design to the horizontal 2-cylinder engine.

In 1906 a vertical-engined car was introduced known as the Vertex and available as either a 20 hp four or 30/40 hp six-cylinder.