Don Smith may refer to:

• Don Carlos Smith (1816–1841), American leader, missionary, and periodical editor in the early days of the Latter Day Saints movement
• Don Smith (ice hockey, born 1887) (1887–1959), Canadian ice hockey player
• Don Smith (author), (1909–?), Canadian journalist and author of spy novels
• Don Smith (basketball, born 1910) (1910–1994), American college basketball player at the University of Pittsburgh
• Don Smith (basketball, born 1920) (1920–1996), American basketball player with the Minneapolis Lakers
• Don Smith (ice hockey, born 1929) (1929–2002), Canadian ice hockey player with the New York Rangers
• Don Smith (motorcyclist) (1937–2004), British motorcycle trials rider
• Zaid Abdul-Aziz (born 1946), American basketball player, born Don Smith
• Don Smith (basketball, born 1951) (1951–2004), American basketball player with the Philadelphia 76ers
• Don Smith (defensive lineman) (born 1957), American football defensive lineman
• Don Smith (boxer) (born 1963), Trinidad and Tobago boxer
• Don Smith (running back) (born 1963), American football running back
• Don Smith (rower) (born 1968), American rower
• Don Smith (songwriter), co-writer of the popular song "Double Shot (Of My Baby's Love)"