Manuel Díaz may refer to:

• Manuel Díaz (fencer) (1874–1929), Cuban fencer who competed at the 1904 Summer Olympics
• Manuel Diaz (tennis), Puerto Rican tennis player and coach
• Manuel Díaz (Mexican cyclist) (1899–?), Mexican cyclist who competed at the 1932 Summer Olympics
• Manuel Díaz Gil (1929–1966), Spanish footballer
• Manuel Díaz Montava (born 1957), Spanish Paralympic cyclist
• Manuel Díaz Vega (born 1954), Spanish football referee