Lafargue or LaFargue may refer to:

• Adolphe Lafargue (1855–1917), Louisiana newspaper publisher, state legislator, and judge
• Alvan Lafargue (1883–1963), Louisiana physician, politician, and civic leader
• André Lafargue (1917–2017), French journalist and theatre critic
• Édouard Lafargue (1803–1884), French playwright
• John Baptist Lafargue (1864–?), American educator, newspaper publisher
• Malcolm Lafargue (1908–1963), Louisiana lawyer and politician
• Paul Lafargue (1842–1911), French revolutionary Marxist
• Quentin Lafargue (born 1990), French racing cyclist
• Simone Iribarne Lafargue (1914–2010), French tennis player