Segers is a Dutch patronymic surname. The mostly archaic Dutch given names Seger, Segher, Sieger and Zegher derive from Germanic Sigi- and -her, meaning "victorious lord". People with the surname Segers include

• Carlos Segers (1900–1967), Argentine astronomer
• Geno Segers (born 1978), American actor
• Gert-Jan Segers (born 1969), Dutch political scientist and politician
• Gunter Segers (born 1968), Belgian children's book author and illustrator
• Gustaaf Segers (1848–1930), Belgian writer and scholar
• Hans Segers (born 1961), Dutch goalkeeper
• Hercules Segers (1589–1638), Dutch painter and printmaker
• Jan Segers (born 1929), Belgian composer, conductor and reed player
• Noël Segers (born 1959), Belgian racing cyclist
• Paul Segers (1870–1946), Belgian government minister
• Paul-Willem Segers (1900–1983), Belgian government minister
• Willy Segers (born 1958), Belgian politician