Kristof Vandewalle (born 5 April 1985) is a Belgian former professional road cyclist, who rode professionally between 2008 and 2015 for the Topsport Vlaanderen–Mercator, Omega Pharma–Quick-Step and Trek Factory Racing teams. While a member of the Omega Pharma–Quick-Step squad, he won two successive World Team Time Trial Championships and two consecutive Belgian National Time Trial Championships.

In the 2014 season, Vandewalle was riding for Trek Factory Racing, after three seasons with Omega Pharma–Quick-Step and its precursor Quick-Step. His first victory in the team's colours was a third national time trial championships in May 2014, in Hooglede.